HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Nitrobenzoic acid → Carnosine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Nitrobenzoic acid | HCID 8497 | — |
| Reactant | Tetramethylammonium hydroxide | HCID 60966 | — |
| Reactant | 1,3-thiazinane-2,4-dione | HCID 2304067 | — |
| Reactant | HCID 178419078 | HCID 178419078 | — |
| Product | Carnosine | HCID 439224 | — |
Reaction Steps
Following the procedure of Example 1, 1.55 g. (10 mmol) of L-histidine and 2.62 g. (20 mmol) of tetrahydro-1,3-thiazin-2,4-dione are reacted, using 40% aqueous tetramethylammonium hydroxide solution to raise pH and m-nitrobenzoic acid to lower pH, to give L-carnosine in good yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04359416 |
| Source dataset | uspto-grants-1982_11 |
| ORD ID | ord-d96d20c8a1134f2a9462773eee4b1b94 |
| Source note | uspto-grants-1982_11 |