Diazomethane → HCID 86737948, compound

HRID 2198779Notes

Reaction equation

HRID 2198779 reaction equation
[Cl:1]/[C:2](/[CH3:9])=[CH:3]\[CH2:4][CH2:5][C:6]([OH:8])=[O:7].[N+](=[CH2:12])=[N-]>CCOCC>[CH3:12][O:7][C:6](=[O:8])[CH2:5][CH2:4]/[CH:3]=[C:2](\[Cl:1])/[CH3:9]

Participants

4

Reactant 2

HCID 9550DiazomethaneHCID 20435364HCID 20435364, compound

Product 1

HCID 86737948HCID 86737948, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

A solution of 10.4 g. of the carboxylic acid prepared according to (c) in 50 ml. of ether was combined with such an amount of ethereal diazomethane solution that there was no longer any liberation of nitrogen during the addition of the reagent and the yellow coloring of the reaction solution remained. Excess diazomethane and solvent were then removed under vacuum, and the residue was distilled with the aid of a water jet aspirator, thus obtaining 10.6 g. of final product, b.p. 87°-89° (18 mm.).

Workup

  1. additionduring the addition of the reagent
  2. customExcess diazomethane and solvent were then removed under vacuum
  3. distillationthe residue was distilled with the aid of a water jet aspirator
  4. customthus obtaining 10.6 g

Sources & evidence

ORD record
ord-48f35ad2f6414f7bad1ea922c12ea50e
Source dataset
uspto-grants-1982_11
Patent number
US04359467

Reaction notes

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