2-bromocyclododecanone → HCID 53838207, compound

HRID 2198822Notes

Reaction equation

HRID 2198822 reaction equation
[CH2:1]1[CH2:13][CH2:12][CH2:11][CH2:10][CH:9](Br)[C:7](=[O:8])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[CH3:15][O:16][C:17](=[O:23])[CH2:18][C:19]([O:21][CH3:22])=[O:20].[Na]>CO>[CH3:15][O:16][C:17](=[O:23])[CH:18]([CH:9]1[CH2:10][CH2:11][CH2:12][CH2:13][CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][C:7]1=[O:8])[C:19]([O:21][CH3:22])=[O:20]

Participants

4

Reactant 2

HCID 357602-bromocyclododecanoneHCID 86741238HCID 86741238, compound

Product 1

HCID 53838207HCID 53838207, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

reacting α-bromocyclododecanone with sodium malonic acid dimethyl ester in methanol at from about 10° to 40° C. to form 2-(2-oxocyclododec-1-yl)-malonic acid dimethyl ester;

Workup

  1. customat from about 10° to 40° C.

Sources & evidence

ORD record
ord-ea9d7da1b94f4775ae421caebf520754
Source dataset
uspto-grants-1982_11
Patent number
US04360468

Reaction notes

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