3-Fluorobenzaldehyde → HCID 13064591, compound

Participants

Reaction Steps

A 7.0 g. amount of N'-(4-amino-2,6-dichlorophenyl)-N,N-dimethylformamidine (Example 9) is dissolved in 25 ml. of absolute ethanol then 3.7 g. of m-fluorobenzaldehyde is added and the mixture is refluxed for one hour. The solution is evaporated to an amber syrup which crystallizes. The material is dissolved in 50 ml. of refluxing ether and hexane is added until turbidity results. The crystalline product is collected and washed with hexane. The product is recrystallized from ether/hexane to give 1.4 g. of the product of the Example as hard yellow crystals, m.p. 95°-96° C.

Provenance & Evidence