Ethanol → HCID 13064594, compound

Participants

Reaction Steps

A mixture of 9.3 g. of N'-(4-amino-2,6-dichlorophenyl)-N,N-dimethylformamidine (Example 9) and 5.0 g. of o-fluorobenzaldehyde in 25 ml. of absolute ethanol is refluxed for 18 hours. The solution is evaporated in vacuo to provide a syrup. The syrup is dissolved in 50 ml. of ether and n-hexane is added to 500 ml. The solution is cooled and filtered. The filtrate is evaporated to 100 ml. to precipitate the product. The product is collected by filtration and washed with n-hexane to give 7.4 g. of the desired product as bright yellow crystals, m.p. 79°-81° C.

Provenance & Evidence