HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2198856Generated: October 26, 2026
Isopropylamine → 1-(Iso-propyl)-3-benzyloxyazetidine
https://huagongshe.com/reaction/2198856
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Isopropylamine | HCID 6363 | — |
| Reactant | (((1,3-Dibromopropan-2-yl)oxy)methyl)benzene | HCID 561824 | — |
| Solvent | Water | HCID 962 | — |
| Product | 1-(Iso-propyl)-3-benzyloxyazetidine | HCID 20517324 | — |
Reaction Steps
11 Parts of 2-benzyloxy-1,3-dibromo-propane, 30 parts of iso-propylamine and 30 parts of water were added to a stainless autoclave, and the mixture was heated at 80° C. for 2 hours with agitation. The reaction mixture was cooled and treated in the same manner as in Example 29, followed by distillation under reduced pressure. As a result, 18 parts of 3-benzyloxy-1-(iso-propyl)azetidine boiling at 104°-107° C. under 2 mm Hg were obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04360464 |
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| Source dataset | uspto-grants-1982_11 |
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| ORD ID | ord-254474e6da6d4692a5dc96eee36f2060 |
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| Source note | uspto-grants-1982_11 |
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