2-Iodotoluene → 2-Iodobenzyl Bromide

HRID 2198862Notes

Reaction equation

HRID 2198862 reaction equation
I[C:2]1[CH:9]=[CH:8][C:5]([CH2:6][Br:7])=[CH:4][CH:3]=1.[I:10]C1C=CC=CC=1C>>[I:10][C:8]1[CH:9]=[CH:2][CH:3]=[CH:4][C:5]=1[CH2:6][Br:7]

Participants

3

Reactant 2

HCID 51282-IodotolueneHCID 9542584-Iodobenzyl bromide

Product 1

HCID 114264722-Iodobenzyl Bromide

Procedure

o-Iodobenzyl bromide was prepared by the procedure described by H. A. Sloviter, J. Am. Chem. Soc. 71, p.3360 (1949) for p-iodobenzyl bromide by starting with o-iodotoluene. The crude product was distilled at reduced pressure to yield a liquid product, bp. 85°-92°/0.5 mm Hg, which crystallized spontaneously to yield a solid product having a mp of 42°-49°.

Workup

  1. distillationThe crude product was distilled at reduced pressure
  2. customto yield a liquid product, bp. 85°-92°/0.5 mm Hg, which
  3. customcrystallized spontaneously
  4. customto yield a solid product

Sources & evidence

ORD record
ord-bae6a39acc34430ca9e1ff9f19ba58b6
Source dataset
uspto-grants-1982_11
Patent number
US04360511

Reaction notes

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