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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2198865Generated: November 1, 2026

Benzyl Chloride → Ethylamine

https://huagongshe.com/reaction/2198865

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzyl ChlorideHCID 7503—
Reactant4-IodoanilineHCID 10893—
ProductEthylamineHCID 6341—
Product1-(Chloromethyl)-2-iodobenzeneHCID 101064—
ProductHCID 12950427HCID 12950427—

Reaction Steps

In a like manner p-iodoaniline and benzyl chloride were reacted to yield N,N-dibenzyl-p-iodoaniline, Rf =0.71, ethylamine and o-iodo-benzyl chloride were reacted to yield N-ethyl-o-iodobenzylamine, Rf =0.55, propylamine and o-iodo-benzyl chloride were reacted to yield N-propyl-o-iodobenzylamine, Rf =0.67, p-iodo-aniline and phenethyl bromide were reacted to yield N-β-phenethyl-p-iodoaniline, Rf =0.73, β-phenethylamine and o-iodobenzyl bromide were reacted to yield N-β-phenethyl-o-iodobenzylamine, Rf =0.64, N-β-phenethyl-o-iodo-benzylamine and phenethyl bromide were reacted to yield N,N-di-β-phenethyl-o-iodobenzylamine, Rf =0.64, ethylamine and o-iodobenzyl chloride were reacted to yield N,N-di-o-iodobenzylethylamine, Rf =0.80, 2,5-dimethylpyrrolidine and o-iodobenzyl chloride were reacted to yield N-o-iodobenzyl-2,5-dimethylpyrrolidine, Rf =0.78, and N-isopropyl-β-phenethylamine and o-iodo-benzyl bromide were reacted to yield N-β-phenethyl-o-iodo-β-phenethylamine, Rf =0.66.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04360511
Source datasetuspto-grants-1982_11
ORD IDord-290e81f2f06a429881aabb4cc656280d
Source noteuspto-grants-1982_11