Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Benzyl Chloride | HCID 7503 | — |
| Reactant | 4-Iodoaniline | HCID 10893 | — |
| Product | Ethylamine | HCID 6341 | — |
| Product | 1-(Chloromethyl)-2-iodobenzene | HCID 101064 | — |
| Product | HCID 12950427 | HCID 12950427 | — |
Reaction Steps
In a like manner p-iodoaniline and benzyl chloride were reacted to yield N,N-dibenzyl-p-iodoaniline, Rf =0.71, ethylamine and o-iodo-benzyl chloride were reacted to yield N-ethyl-o-iodobenzylamine, Rf =0.55, propylamine and o-iodo-benzyl chloride were reacted to yield N-propyl-o-iodobenzylamine, Rf =0.67, p-iodo-aniline and phenethyl bromide were reacted to yield N-β-phenethyl-p-iodoaniline, Rf =0.73, β-phenethylamine and o-iodobenzyl bromide were reacted to yield N-β-phenethyl-o-iodobenzylamine, Rf =0.64, N-β-phenethyl-o-iodo-benzylamine and phenethyl bromide were reacted to yield N,N-di-β-phenethyl-o-iodobenzylamine, Rf =0.64, ethylamine and o-iodobenzyl chloride were reacted to yield N,N-di-o-iodobenzylethylamine, Rf =0.80, 2,5-dimethylpyrrolidine and o-iodobenzyl chloride were reacted to yield N-o-iodobenzyl-2,5-dimethylpyrrolidine, Rf =0.78, and N-isopropyl-β-phenethylamine and o-iodo-benzyl bromide were reacted to yield N-β-phenethyl-o-iodo-β-phenethylamine, Rf =0.66.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04360511 |
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| Source dataset | uspto-grants-1982_11 |
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| ORD ID | ord-290e81f2f06a429881aabb4cc656280d |
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| Source note | uspto-grants-1982_11 |
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