HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,3-Dichloro-5,6-dicyano-1,4-benzoquinone → HCID 86738646, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,3-Dichloro-5,6-dicyano-1,4-benzoquinone | HCID 6775 | — |
| Reactant | HCID 86738648 | HCID 86738648 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 86738646 | HCID 86738646 | — |
Reaction Steps
Analogously to Example 12, 200 mg of 21-chloro-6α-fluoro-17α-hydroxy-16β-methyl-pregn-4-ene-3,20-dione propionate (see Example 10) are treated with 250 mg of 2,3-dichloro-5,6-dicyano-1,4-benzoquinone in 8 ml of dioxan and further processed to yield 21-chloro-6α-fluoro-17α-hydroxy-16β-methyl-pregna-1,4-diene-3,20-dione propionate; melting point 216°-219° C. (from methylene chloride/ether).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04361558 |
| Source dataset | uspto-grants-1982_11 |
| ORD ID | ord-42b776d27d614694888846ac2f25e092 |
| Source note | uspto-grants-1982_11 |