HCID 86738654, compound → HCID 67880269, compound

Participants

Reaction Conditions

Reaction Steps

A suspension of 5.2 g of 11β-acetyloxy-17,17-bis(ethylthio)-9-fluoroandrosta-1,4-dien-3-one in 85 ml of dry diethylbenzene is stirred at 180° C. (oil bath temperature) for 1.0 hour; the suspension gradually becomes a homogeneous solution during the heating. The resulting solution is cooled to 0° C. and the solid that precipitates is filtered and dried in vacuo to give 3.6 g of the title compound, melting point 211°-215° C., with consistent spectral data.

Provenance & Evidence