HCID 86735751, compound → HCID 70463489, compound

Participants

Reaction Conditions

Reaction Steps

A suspension of 1.5 g of 11β-acetyloxy-17,17-bis(phenylthio)-9-fluoroandrosta-1,4-dien-3-one in 25 ml of dry diethylbenzene is stirred at 185°-190° C. (oil bath temperature) for 1.0 hour. The suspension gradually becomes a homogeneous solution during the heating and the resulting solution is cooled to 0° C. The solid that precipitates is filtered and dried in vacuo to give 0.9 g of the title compound, melting point 228°-229° C., with consistent spectral data.

Provenance & Evidence