HCID 86738658, compound → HCID 70464920, compound

Participants

Reaction Conditions

Reaction Steps

A suspension of 4.4 g of 17,17-bis(ethylthio)-11β-hydroxyandrosta-1,4-dien-3-one (see example 2) in 100 ml of dry diethyl benzene is stirred at 190°-195° C. (oil bath temperature) for 1.5 hours. The suspension becomes a solution during the heating; the resulting solution is cooled to 0° C. The solid that precipitates is filtered and dried in vacuo to give 3.0 g of the title compound, melting point 216°-218° C., with consistent spectral data.

Provenance & Evidence