Hydrochloric Acid → HCID 71230788, compound

Participants

Reaction Conditions

Reaction Steps

Intermediate D (1.10 g, 2.00 mmol) was dissolved in dioxane (5 ml) and 2 M NaOH (5 ml) was added. The mixture was heated at 80° C. for 1 h. 6 M HCl was added and the aqueous mixture extracted with EtOAc. Combined organic layers were dried (MgSO4) and evaporated. Yield: 982 mg (94%); pale yellow solid. 1H NMR (400 MHz, DMSO-d6): δ 3.77 (s, 4H), 7.30 (s, 2H), 7.31 (s, 2H).

Provenance & Evidence