Hydrochloric Acid → HCID 71230627, compound

Participants

Reaction Steps

Intermediate C (71 mg, 0.181 mmol) was dissolved in dioxane (2 ml) and 1 M NaOH (0.40 ml) and the mixture was stirred at rt overnight. The mixture was acidified by 1 M HCl and aqueous layer extracted with EtOAc. The organic layer was dried (MgSO4) and filtered. Yield: 57 mg (87%); yellow soid. 1H NMR (400 HMz, DMSO-d6): δ 3.73 (s, 4H), 7.09 (d, J 5.2 Hz, 2H), 7.23 (s, 2H), 7.53 (d, J 5.2 Hz, 2H), 12.52 (s, 2H).

Provenance & Evidence