HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triphenylphosphine → (3-(7-bromo-2-(ethoxycarbonyl)-1H-indol-3-yl)propyl)triphenylphosphonium iodide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triphenylphosphine | HCID 11776 | — |
| Reactant | ethyl 7-bromo-3-(3-iodopropyl)-1H-indole-2-carboxylate | HCID 68936016 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | (3-(7-bromo-2-(ethoxycarbonyl)-1H-indol-3-yl)propyl)triphenylphosphonium iodide | HCID 87628294 | — |
Reaction Steps
To a mixture of EXAMPLE 111A (0.136 g) in CH3CN (5 mL) was added triphenylphosphine (157 mg). The mixture was refluxed for 48 hours, cooled to room temperature, washed with hexanes and concentrated.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09359296B2 |
| Source dataset | uspto-grants-2016_06 |
| ORD ID | ord-7cfebf82afd14953b5d5e842a30395da |
| Source note | uspto-grants-2016_06 |