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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2199916Generated: October 31, 2026

Benzene, 1-(chloromethyl)-2-fluoro- → 2-(1-benzyl-1H-indole-6-yl)acetic acid

https://huagongshe.com/reaction/2199916

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzene, 1-(chloromethyl)-2-fluoro-HCID 9580—
Reactant2-(1-benzyl-1H-indole-6-yl)acetic acidHCID 54488924—
Product2-(1-benzyl-1H-indole-6-yl)acetic acidHCID 54488924—
Product2-[1-(2-fluorobenzyl)-1H-indole-6-yl]acetic acidHCID 68184485—

Reaction Steps

The titled compound (22 mg) as a white solid was prepared from the compound [4-6] obtained in the process (6) of Example 4 (100 mg) and 2-fluorobenzyl chloride according to the method of the process (7) of Example 4.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09359350B2
Source datasetuspto-grants-2016_06
ORD IDord-acbf03d88b9347668f364db6932dcbce
Source noteuspto-grants-2016_06