HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(Bromomethyl)-1-fluoro-3-(trifluoromethyl)benzene → 2-(1-benzyl-1H-indole-6-yl)acetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(Bromomethyl)-1-fluoro-3-(trifluoromethyl)benzene | HCID 2737573 | — |
| Reactant | 2-(1-benzyl-1H-indole-6-yl)acetic acid | HCID 54488924 | — |
| Product | 2-(1-benzyl-1H-indole-6-yl)acetic acid | HCID 54488924 | — |
| Product | 2-{1-[2-fluoro-6-(trifluoromethyl)benzyl]-1H-indole-6-yl}acetic acid | HCID 68183776 | — |
Reaction Steps
The titled compound (16 mg) as a white solid was prepared from the compound [4-6] obtained in the process (6) of Example 4 (100 mg) and 2-fluoro-6-(trifluoromethyl)benzyl bromide according to the method of the process (7) of Example 4.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09359350B2 |
| Source dataset | uspto-grants-2016_06 |
| ORD ID | ord-9d71fa7e3b7a40ab8f033c3e8b60224d |
| Source note | uspto-grants-2016_06 |