Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2199937Generated: October 30, 2026

p-Trifluoromethylbenzyl chloride → 2-(1-benzyl-1H-indole-6-yl)acetic acid

https://huagongshe.com/reaction/2199937

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-Trifluoromethylbenzyl chlorideHCID 123096—
Reactant2-(1-benzyl-1H-indole-6-yl)acetic acidHCID 54488924—
Product2-(1-benzyl-1H-indole-6-yl)acetic acidHCID 54488924—
ProductHCID 68184487HCID 68184487—

Reaction Steps

The titled compound (33 mg) as a white solid was prepared from the compound [4-6] obtained in the process (6) of Example 4 (100 mg) and 4-(trifluoromethyl)benzyl chloride according to the method of the process (7) of Example 4.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09359350B2
Source datasetuspto-grants-2016_06
ORD IDord-3f7a4429e65d44249e6458e0f3271665
Source noteuspto-grants-2016_06