Acetic acid, 2-(triphenylphosphoranylidene)-, methyl ester → HCID 13707694, compound

Participants

Reaction Steps

To a solution of indole-6-carboxaldehyde (499 mg) in tetrahydrofuran (20 mL), methyl(triphenylphosphoranylidene)acetate (2.5 g) was added at room temperature, and then the reaction mixture was subjected to microwave irradiation at 200° C. for 20 minutes. The reaction mixture was concentrated under reduced pressure, and the obtained residue was purified by silica gel column chromatography to give the titled compound (501 mg) as a yellow solid.

Provenance & Evidence