HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-benzyl-1H-indole-6-carboxylic acid → HCID 178437984, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-benzyl-1H-indole-6-carboxylic acid | HCID 17947875 | — |
| Reactant | 5-Bromo-3-fluoropyridine-2-carbonitrile | HCID 44196680 | — |
| Reactant | 1-(2,6-dimethylbenzyl)-1H-indole-6-carboxylic acid | HCID 68184345 | — |
| Reactant | HCID 178461633 | HCID 178461633 | — |
| Product | HCID 178437984 | HCID 178437984 | — |
Reaction Steps
The titled compound (225 mg) as a white solid was prepared from 5-bromo-3-fluoropyridin-2-carbonitrile (201 mg) obtained by the method described in the document (Journal of Organic Chemistry, 2009, Vol. 74, p. 4547) and ethylmagnesium chloride according to the methods of the processes (1) and (2) of Example 153.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09359350B2 |
| Source dataset | uspto-grants-2016_06 |
| ORD ID | ord-9fa6f0eb43a14b7bb1d1afa5a02281e0 |
| Source note | uspto-grants-2016_06 |