Potassium Hydroxide → HCID 131732626, compound

HRID 2199997Notes

Reaction equation

HRID 2199997 reaction equation
[Cl:1][C:2]1[C:6]2=[N:7][CH:8]=[C:9]([C:11]([OH:13])=[O:12])[CH:10]=[C:5]2[N:4]([CH2:14][C:15]2[C:20]([Cl:21])=[CH:19][CH:18]=[CH:17][C:16]=2[Cl:22])[N:3]=1.[OH-].[K+:24]>C(O)C>[Cl:1][C:2]1[C:6]2=[N:7][CH:8]=[C:9]([C:11]([O-:13])=[O:12])[CH:10]=[C:5]2[N:4]([CH2:14][C:15]2[C:16]([Cl:22])=[CH:17][CH:18]=[CH:19][C:20]=2[Cl:21])[N:3]=1.[K+:24]

Participants

4

Reactant 2

HCID 14797Potassium HydroxideHCID 60152280HCID 60152280, compound

Product 1

HCID 131732626HCID 131732626, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

To a solution of the compound [172] (27 mg) in ethanol (2.0 mL) was added an aqueous solution of 1N-potassium hydroxide (74 μL) at room temperature, and the solution was concentrated under reduced pressure to give the titled compound (28 mg) as a white solid.

Workup

  1. concentrationthe solution was concentrated under reduced pressure

Sources & evidence

ORD record
ord-83489ad21066413c802fdfb8a62667fa
Source dataset
uspto-grants-2016_06
Patent number
US09359350B2

Reaction notes

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