Benzylamine → HCID 178420343, compound

Participants

Reaction Steps

In another aspect, a process for preparing a compound of Formula (II) is described, comprising: (a) condensing benzylamine with cyclohex-3-enecarbaldehyde to form (E)-N-(cyclohex-3-en-1-ylmethylene)-1-phenylmethanamine; (b) contacting (E)-N-(cyclohex-3-en-1-ylmethylene)-1-phenylmethanamine with an isomerizing agent to form (E)-N-benzylidene-1-(cyclohex-3-en-1-yl)methanamine; (c) contacting (E)-N-benzylidene-1-(cyclohex-3-en-1-yl)methanamine with an aldehyde, or with an acetal, or with a hemiacetal, in presence of formic acid and a reaction medium to form a compound of Formula (I); and (d) contacting a compound of Formula (I) with a hydrolyzing agent.

Provenance & Evidence