HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 117728990, compound → Methanesulfonic acid 2-{3-[3-(cyano-dimethyl-methyl)-5-(3-{(1S,4R)-4-[3-((2S,6R)-2,6-dimethyl-piperidin-1-yl)-[1,2,4]triazolo[4,3-a]pyridin-6-yloxy]-1,2,3,4-tetrahydro-naphthalen-1-yl}-ureido)-pyrazol-1-yl]-phenoxy}-ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 117728990 | HCID 117728990 | — |
| Reactant | 1-{5-(Cyano-dimethyl-methyl)-2-[3-(2-hydroxy-ethoxy)-phenyl]-2H-pyrazol-3-yl}-3-{(1S,4R)-4-[3-((2S,6R)-2,6-dimethyl-piperidin-1-yl)-[1,2,4]triazolo[4,3-a]pyridin-6-yloxy]-1,2,3,4-tetrahydro-naphthalen-1-yl}-urea | HCID 117729326 | — |
| Product | Methanesulfonic acid 2-{3-[3-(cyano-dimethyl-methyl)-5-(3-{(1S,4R)-4-[3-((2S,6R)-2,6-dimethyl-piperidin-1-yl)-[1,2,4]triazolo[4,3-a]pyridin-6-yloxy]-1,2,3,4-tetrahydro-naphthalen-1-yl}-ureido)-pyrazol-1-yl]-phenoxy}-ethyl ester | HCID 117729092 | — |
Reaction Steps
The title compound was prepared using Intermediate 21a in an analogous fashion to the procedures described for Intermediate A step e. LCMS (Method 3): Rt 3.85 min, m/z 782.5 [MH+].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09359354B2 |
| Source dataset | uspto-grants-2016_06 |
| ORD ID | ord-20dc621dd10a4b8d82b58e3a1192e455 |
| Source note | uspto-grants-2016_06 |