HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzophenone imine → HCID 118223425, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzophenone imine | HCID 136809 | — |
| Reactant | 1,1'-(9,9-Dimethyl-9H-xanthene-4,5-diyl)bis(1,1-diphenylphosphine) | HCID 636044 | — |
| Reactant | Potassium tert-butoxide | HCID 23665647 | — |
| Reactant | HCID 90020675 | HCID 90020675 | — |
| Catalyst | palladium(II) acetate | HCID 167845 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 118223425 | HCID 118223425 | — |
Reaction Steps
Mix the cyclopropanecarboxamide derivative obtained in Step 2 (400 mg, 1.15 mmol), benzophenone imine (624 mg, 3.45 mmol), t-BuOK (257 mg, 2.3 mmol) and 1,4-dioxane in a 250 mL flask, add Xantphos (133 mg, 0.23 mmol), Pd(OAc)2 (26 mg, 0.115 mmol). Stir the reaction under N2 at 120° C. for 15 hrs.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09359338B2 |
| Source dataset | uspto-grants-2016_06 |
| ORD ID | ord-50c06dc937b94eb68ba0370f71c38d34 |
| Source note | uspto-grants-2016_06 |