HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 5-bromopyridine-3-carboxylate → Methyl 5-(4-ethylphenyl)pyridine-3-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 5-bromopyridine-3-carboxylate | HCID 699336 | — |
| Reactant | Boronic acid, (4-ethylphenyl)- | HCID 2734352 | — |
| Product | Methyl 5-(4-ethylphenyl)pyridine-3-carboxylate | HCID 58002322 | — |
Reaction Steps
According to General Method 3A, 32 g (148 mmol) of methyl 5-bromonicotinate and 27 g (178 mmol, 1.2 eq.) of 4-ethylphenylboronic acid were reacted. Yield: 24 g (64% of theory)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08202862B2 |
| Source dataset | uspto-grants-2012_06 |
| ORD ID | ord-b6e49e33a74f4231b8f1b4a940e0c780 |
| Source note | uspto-grants-2012_06 |