HCID 131735708, compound → HCID 118105554, compound

Participants

Reaction Steps

To a solution of (1S,3S)-benzyl 3-(4-(4-fluorophenyl)piperazin-1-yl)cyclopentanecarboxylate (0.6 g, 0.52 mmol) in methanol (15 ml) was added 10% palladium on charcoal (60 mg). The reaction mixture was stirred at room temperature under H2 atmosphere at atmospheric pressure for 2 h. Upon completion, the reaction mixture was filtered through a pad of celite, and washed with methanol (15 ml). The filtrate was concentrated under reduced pressure to afford the title compound (0.4 g, 87%), which was used further without purification.

Provenance & Evidence