Dichloromethane → HCID 90449331, compound

Participants

Reaction Steps

In DCM (10 mL) was dissolved tert-butyl 4-(9-(6-methoxypyridin-3-yl)-3-methyl-2-oxo-3,4-dihydropyrimido[5,4-c][1,5]naphthyridin-1(2H)-yl)piperidine-1-carboxylate (75 mg, 0.149 mmol). The solution was purged with hydrogen chloride gas for 0.5 h and a precipitate was formed. The precipitate was filtrated under reduced pressure, washed sequentially with DCM and diethyl ether and dried to give a solid (50 mg, 76.1% yield).

Provenance & Evidence