HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thiourea → 2-(((4-Methoxybenzyl)oxy)methyl)thiirane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thiourea | HCID 2723790 | — |
| Reactant | 2-(((4-Methoxyphenyl)methoxy)methyl)oxirane | HCID 2774076 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 2-(((4-Methoxybenzyl)oxy)methyl)thiirane | HCID 86723459 | — |
Reaction Steps
Thiourea (0.935 g, 12.28 mmol) was added to a solution of 2-(((4-methoxybenzyl)oxy)methyl) oxirane (1.084 g, 5.58 mmol) in methanol (30 mL) and the mixture stirred at room temperature for 16 hours, then evaporated under vacuum. Purification by chromatography on silica, eluting with 0-10% EtOAc/hexane, afforded the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09359381B2 |
| Source dataset | uspto-grants-2016_06 |
| ORD ID | ord-e9d26d5a7c654119a2eed201ab8cc254 |
| Source note | uspto-grants-2016_06 |