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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2201238Generated: October 29, 2026

3-Iodo-1-methyl-1H-pyrazole → 1,3-Dimethyl-5-(1-methyl-1H-pyrazol-3-yl)-1H-pyrrolo[3,4-d]pyrimidine-2,4(3H,6H)-dione

https://huagongshe.com/reaction/2201238

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Iodo-1-methyl-1H-pyrazoleHCID 13334057—
Reactant3-(1,3-Dimethyl-2,4-dioxo-2,3,4,6-tetrahydro-1H-pyrrolo[3,4-d]pyrimidin-5-yl)benzonitrileHCID 86722928—
Product1,3-Dimethyl-5-(1-methyl-1H-pyrazol-3-yl)-1H-pyrrolo[3,4-d]pyrimidine-2,4(3H,6H)-dioneHCID 136348407—

Reaction Steps

The title compound was prepared by a similar method to 3-(1,3-Dimethyl-2,4-dioxo-2,3,4,6-tetrahydro-1H-pyrrolo[3,4-d]pyrimidin-5-yl)benzonitrile (Example 9.0 Step 4), replacing 3-bromobenzonitrile with 3-iodo-1-methyl-1H-pyrazole in Step 3.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09359381B2
Source datasetuspto-grants-2016_06
ORD IDord-6454ca3e441d42baa02a408714cb70b2
Source noteuspto-grants-2016_06