HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Bromo-3-fluorobenzene → 5-(3-fluorophenyl)-1,3-dimethyl-1H-pyrrolo[3,4-d]pyrimidine-2,4(3H,6H)-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Bromo-3-fluorobenzene | HCID 14082 | — |
| Reactant | 3-(1,3-Dimethyl-2,4-dioxo-2,3,4,6-tetrahydro-1H-pyrrolo[3,4-d]pyrimidin-5-yl)benzonitrile | HCID 86722928 | — |
| Product | 5-(3-fluorophenyl)-1,3-dimethyl-1H-pyrrolo[3,4-d]pyrimidine-2,4(3H,6H)-dione | HCID 86722930 | — |
Reaction Steps
The title compound was prepared analogously to 3-(1,3-Dimethyl-2,4-dioxo-2,3,4,6-tetrahydro-1H-pyrrolo[3,4-d]pyrimidin-5-yl)benzonitrile (Example 9.0 Step 4) by replacing 3-bromobenzonitrile by 3-fluoro-1-bromobenzene in step 3;
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09359381B2 |
| Source dataset | uspto-grants-2016_06 |
| ORD ID | ord-3d6913e659f24a6b8b656754786e0076 |
| Source note | uspto-grants-2016_06 |