HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2201482Generated: October 29, 2026
HCID 53212388, compound → HCID 67975090, compound
https://huagongshe.com/reaction/2201482
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | HCID 53212388 | HCID 53212388 | — |
| Reactant | 4-(4,4,5,5-Tetramethyl-(1,3,2)dioxaborolan-2-yl)cyclohex-3-ene-1-carboxylic acid ethyl ester | HCID 59278796 | — |
| Product | HCID 67975090 | HCID 67975090 | 55% |
Reaction Steps
Followed the coupling procedure similar to that described in Compound VIII-2 (Example 65), where the starting materials were ethyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohex-3-enecarboxylate and 2-chloro-6-methoxy-3-(trifluoromethyl)quinoxaline (Intermediate 11) and where the reaction here was stirred under N2 atmosphere at 100° C. for 3 hours. Ethyl 4-(6-methoxy-3-(trifluoromethyl)quinoxalin-2-yl)cyclohex-3-enecarboxylate was isolated (800 mg, yield 55%) as yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US09364481B2 |
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| Source dataset | uspto-grants-2016_06 |
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| ORD ID | ord-71e0df2cfe1c471d9a386e1277323796 |
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| Source note | uspto-grants-2016_06 |
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