Ammonium Chloride → HCID 89880880, compound

Participants

Reaction Steps

Subsequently, N-[2-(4-nitrophenyl)ethyl]methacrylamide (1.20 g) was dissolved in ethanol (15 mL) and water (5 mL). Ammonium chloride (364 mg) and iron powder (933 mg) were added, and the reflux was performed at 80° C. for 4 hours. Iron powder was collected by the filtration, and the filtrate was evaporated under the reduced pressure. Water and ethyl acetate were added to the residual oil and the organic layer was separated. The organic layer was washed with water and brine, dried over anhydrous sodium filfate, and evaporated to give the desired compound as a pale red oily substance. The yield was 1.01 g (97%). Spectrum data of 1H-NMR (400 MHz, CDCl3) is shown for the obtained compound.

Provenance & Evidence