HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diisopropylethylamine → HCID 67129270, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | 5-Bromovaleryl chloride | HCID 521173 | — |
| Reactant | Benzyl N-(4-aminophenyl)carbamate | HCID 11253521 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 67129270 | HCID 67129270 | 50% |
Reaction Steps
Aniline 1 (12.69 g, 0.052 mol) was stirred in dichloromethane at 0° C. and 5-bromovaleryl chloride (8.9 mL, 0.052 mol) added followed by diisopropylethylamine (9 mL, 0.052 mol). The resulting white suspension was allowed to warm to room temperature and stirred for 3 h. The white solid was collected by filtration and recrystallised from ethyl acetate to give 2 as a white fluffy powder (10.22 g, 50%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09365508B2 |
| Source dataset | uspto-grants-2016_06 |
| ORD ID | ord-f061b44e73534e80bf7c93964b421c72 |
| Source note | uspto-grants-2016_06 |