Acetamide → N-(1H-Pyrrolo[2,3-c]pyridin-7-yl)acetamide

HRID 2201766Notes

Reaction equation

HRID 2201766 reaction equation
Cl[C:2]1[N:3]=[CH:4][CH:5]=[C:6]2[CH:10]=[CH:9][NH:8][C:7]=12.[C:11]([NH2:14])(=[O:13])[CH3:12]>>[NH:8]1[C:7]2=[C:2]([NH:14][C:11](=[O:13])[CH3:12])[N:3]=[CH:4][CH:5]=[C:6]2[CH:10]=[CH:9]1

Participants

3

Reactant 2

HCID 178AcetamideHCID 114350487-Chloro-1H-pyrrolo[2,3-c]pyridine

Product 1

HCID 86720620N-(1H-Pyrrolo[2,3-c]pyridin-7-yl)acetamideYield 8.69%

Procedure

N-(1H-Pyrrolo[2,3-c]pyridin-7-yl)acetamide (Intermediate 6, yield: 8.69%) was synthesized from 7-chloro-1H-pyrrolo[2,3-c]pyridine using acetamide.

Sources & evidence

ORD record
ord-bbe12b4d477a4a5c8c95ec15f9489c38
Source dataset
uspto-grants-2016_06
Patent number
US09364466B2

Reaction notes

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