Cyclopropanecarboxamide → N-(1H-pyrrolo[2,3-c]pyridin-7-yl)cyclopropanecarboxamide

HRID 2201767Notes

Reaction equation

HRID 2201767 reaction equation
Cl[C:2]1[N:3]=[CH:4][CH:5]=[C:6]2[CH:10]=[CH:9][NH:8][C:7]=12.[CH:11]1([C:14]([NH2:16])=[O:15])[CH2:13][CH2:12]1>>[NH:8]1[C:7]2=[C:2]([NH:16][C:14]([CH:11]3[CH2:13][CH2:12]3)=[O:15])[N:3]=[CH:4][CH:5]=[C:6]2[CH:10]=[CH:9]1

Participants

3

Reactant 2

HCID 80376CyclopropanecarboxamideHCID 114350487-Chloro-1H-pyrrolo[2,3-c]pyridine

Product 1

HCID 71061452N-(1H-pyrrolo[2,3-c]pyridin-7-yl)cyclopropanecarboxamideYield 7.59%

Procedure

N-(1H-pyrrolo[2,3-c]pyridin-7-yl)cyclopropanecarboxamide (Intermediate 7, yield: 7.59%) was synthesized from 7-chloro-1H-pyrrolo[2,3-c]pyridine using cyclopropanamide.

Sources & evidence

ORD record
ord-76e803af0e1041bea370ffb197ef16eb
Source dataset
uspto-grants-2016_06
Patent number
US09364466B2

Reaction notes

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