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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2202447Generated: October 26, 2026

4-(1-Pyrrolidinyl)piperidine → 6,6-Dimethyl-11-oxo-8-(4-pyrrolidin-1-yl-piperidin-1-yl)-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile

https://huagongshe.com/reaction/2202447

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(1-Pyrrolidinyl)piperidineHCID 78703—
ReactantTrifluoro-methanesulfonic acid 3-cyano-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazol-8-yl esterHCID 86663817—
Product6,6-Dimethyl-11-oxo-8-(4-pyrrolidin-1-yl-piperidin-1-yl)-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrileHCID 49804866—

Reaction Steps

With the same condition as the method for synthesizing the Compound B2-1, the title compound was synthesized from the Compound B1 and 4-pyrrolidin-1-yl-piperidine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09365514B2
Source datasetuspto-grants-2016_06
ORD IDord-85795114e9ba433784b2eeb06c0dd9e1
Source noteuspto-grants-2016_06