HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-bromo-1-phenyl-1H-benzo[d]imidazole → 1-Phenyl-6-(2-p-tolyl-2H-pyrazol-3-yl)-1H-benzoimidazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-bromo-1-phenyl-1H-benzo[d]imidazole | HCID 20266860 | — |
| Reactant | 1-p-tolyl-1H-pyrazol-5-ylboronic acid | HCID 90095014 | — |
| Product | 1-Phenyl-6-(2-p-tolyl-2H-pyrazol-3-yl)-1H-benzoimidazole | HCID 73673429 | — |
Reaction Steps
The title compound, off-white foam (36 mg, 28%), MS (ISP) m/z=351.3 [(M+H)+], was prepared in accordance with the general method of example 1 from 6-bromo-1-phenyl-1H-benzo[d]imidazole (intermediate E) (100 mg, 366 μmol) and 1-p-tolyl-1H-pyrazol-5-ylboronic acid (intermediate B) (96.2 mg, 476 μmol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09365550B2 |
| Source dataset | uspto-grants-2016_06 |
| ORD ID | ord-e4e0262fc0c04aa2b2e0513e0905094f |
| Source note | uspto-grants-2016_06 |