HuagongsheHuagongshe Chemistry Print Report · For research reference only
(1-phenyl-1H-pyrazol-5-yl)boronic acid → 6-(2-Phenyl-2H-pyrazol-3-yl)-1-p-tolyl-1H-benzoimidazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (1-phenyl-1H-pyrazol-5-yl)boronic acid | HCID 59436217 | — |
| Reactant | 6-bromo-1-p-tolyl-1H-benzo[d]imidazole | HCID 90095458 | — |
| Product | 6-(2-Phenyl-2H-pyrazol-3-yl)-1-p-tolyl-1H-benzoimidazole | HCID 73673430 | — |
Reaction Steps
The title compound, off-white solid (27 mg, 22%), MS (ISP) m/z=351.3 [(M+H)+], mp 146° C., was prepared in accordance with the general method of example 1 from 6-bromo-1-p-tolyl-1H-benzo[d]imidazole (intermediate F) (100 mg, 348 μmol) and commercially available 1-phenyl-1H-pyrazol-5-ylboronic acid [CAS No. 1238702-56-1] (85.1 mg, 453 μmol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09365550B2 |
| Source dataset | uspto-grants-2016_06 |
| ORD ID | ord-f230ab930830466aaba1124b95aa5916 |
| Source note | uspto-grants-2016_06 |