1-p-tolyl-1H-pyrazol-5-ylboronic acid → 1-(4-Fluoro-phenyl)-6-(2-p-tolyl-2H-pyrazol-3-yl)-1H-benzoimidazole

Participants

Reaction Steps

The title compound, light brown foam (78 mg, 61%), MS (ISP) m/z=369.2 [(M+H)+], was prepared in accordance with the general method of example 1 from 6-bromo-1-(4-fluoro-phenyl)-1H-benzo[d]imidazole (intermediate G) (100 mg, 344 μmol) and 1-p-tolyl-1H-pyrazol-5-ylboronic acid (intermediate B) (90.2 mg, 447 μmol).

Provenance & Evidence