6-bromo-1-(4-chloro-phenyl)-1H-benzo[d]imidazole → 1-(4-Chloro-phenyl)-6-[2-(4-trifluoromethyl-phenyl)-2H-pyrazol-3-yl]-1H-benzoimidazole

Participants

Reaction Steps

The title compound, light brown solid (56 mg, 39%), MS (ISP) m/z=439.4 [(M+H)+], mp 198° C., was prepared in accordance with the general method of example 1 from 6-bromo-1-(4-chloro-phenyl)-1H-benzo[d]imidazole (intermediate H) (100 mg, 325 μmol) and 1-(4-trifluoromethyl-phenyl)-1H-pyrazol-5-ylboronic acid (intermediate C) (91.6 mg, 358 μmol).

Provenance & Evidence