HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-bromo-1-(4-chloro-phenyl)-1H-benzo[d]imidazole → 1-(4-Chloro-phenyl)-6-[2-(4-chloro-phenyl)-2H-pyrazol-3-yl]-1H-benzoimidazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-bromo-1-(4-chloro-phenyl)-1H-benzo[d]imidazole | HCID 90095072 | — |
| Reactant | 1-(4-chloro-phenyl)-1H-pyrazol-5-ylboronic acid | HCID 90095126 | — |
| Product | 1-(4-Chloro-phenyl)-6-[2-(4-chloro-phenyl)-2H-pyrazol-3-yl]-1H-benzoimidazole | HCID 73673561 | — |
Reaction Steps
The title compound, light brown solid (29 mg, 22%), MS (ISP) m/z=405.4 [(M+H)+], mp 182° C., was prepared in accordance with the general method of example 1 from 6-bromo-1-(4-chloro-phenyl)-1H-benzo[d]imidazole (intermediate H) (100 mg, 325 μmol) and 1-(4-chloro-phenyl)-1H-pyrazol-5-ylboronic acid (intermediate D) (79.6 mg, 358 μmol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09365550B2 |
| Source dataset | uspto-grants-2016_06 |
| ORD ID | ord-b642c3db32974ecd85b2c7f08b252e86 |
| Source note | uspto-grants-2016_06 |