6-bromo-1-(4-methylsulfonyl-phenyl)-1H-benzo[d]imidazole → 6-[2-(4-Chloro-phenyl)-2H-pyrazol-3-yl]-1-(4-methanesulfonyl-phenyl)-1H-benzoimidazole

Participants

Reaction Steps

The title compound, white solid (13 mg, 15%), MS (ISP) m/z=449.4 [(M+H)+], mp 280° C., was prepared in accordance with the general method of example 1 from 6-bromo-1-(4-methylsulfonyl-phenyl)-1H-benzo[d]imidazole (intermediate O) (70 mg, 199 μmol) and 1-(4-chloro-phenyl)-1H-pyrazol-5-ylboronic acid (intermediate D) (53.2 mg, 239 μmol).

Provenance & Evidence