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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 220248Generated: October 25, 2026

3,5-Diamino-2-methylbenzoic acid → Methyl 2-(3-(methylamino)propyl)-1H-benzo[d]imidazole-5-carboxylate

https://huagongshe.com/reaction/220248

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,5-Diamino-2-methylbenzoic acidHCID 135524—
Reactant[3-(5,6-dimethoxy-1H-benzoimidazol-2-yl)-propyl]-methyl-amineHCID 61363740—
ProductMethyl 2-(3-(methylamino)propyl)-1H-benzo[d]imidazole-5-carboxylateHCID 178483380—

Reaction Steps

Prepared from 3,4-diamino-benzoic acid methyl ester (Eur. J. Med. Chem. 2004, 39(3), 291-298) in analogy to the methods described for [3-(5,6-dimethoxy-1H-benzoimidazol-2-yl)-propyl]-methyl-amine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08202885B2
Source datasetuspto-grants-2012_06
ORD IDord-ed0ebb2e04f9409d9ff17be88a6e3980
Source noteuspto-grants-2012_06