1-(4-Chlorophenyl)-1H-imidazole → 6-[3-(4-Chloro-phenyl)-3H-imidazol-4-yl]-1-(4-fluoro-phenyl)-1H-benzoimidazole

Participants

Reaction Steps

The title compound, off-white solid (20 mg, 15%), MS (ISP) m/z=389.5 [(M+H)+], mp 254° C., was prepared in accordance with the general method of example 28 from 6-bromo-1-(4-fluoro-phenyl)-1H-benzo[d]imidazole (intermediate G) (204 mg, 0.7 mmol) and commercially available 1-(4-chloro-phenyl)-1H-imidazole (62.5 mg, 0.35 mmol).

Provenance & Evidence