HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(4-Fluorophenyl)imidazole → 1-(4-Fluoro-phenyl)-6-[3-(4-fluoro-phenyl)-3H-imidazol-4-yl]-1H-benzoimidazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(4-Fluorophenyl)imidazole | HCID 140833 | — |
| Reactant | 6-bromo-1-(4-fluoro-phenyl)-1H-benzo[d]imidazole | HCID 90095139 | — |
| Product | 1-(4-Fluoro-phenyl)-6-[3-(4-fluoro-phenyl)-3H-imidazol-4-yl]-1H-benzoimidazole | HCID 73671985 | — |
Reaction Steps
The title compound, light brown solid (26 mg, 20%), MS (ISP) m/z=373.5 [(M+H)+], mp 247° C., was prepared in accordance with the general method of example 28 from 6-bromo-1-(4-fluoro-phenyl)-1H-benzo[d]imidazole (intermediate G) (204 mg, 0.7 mmol) and commercially available 1-(4-fluoro-phenyl)-1H-imidazole (56.8 mg, 0.35 mmol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09365550B2 |
| Source dataset | uspto-grants-2016_06 |
| ORD ID | ord-19bcb3f855c7412596bf6a50035b168d |
| Source note | uspto-grants-2016_06 |