Hydrogen Bromide → HCID 90120278, compound

Participants

Reaction Steps

A solution of D6 in DCM (0.2 M) was treated with an excess of HBr solution in AcOH at 0° C. and the reaction mixture was stirred at this temperature for 1 h. Then solvents were removed under reduced pressure and excess reagents were removed by repeated addition of toluene and evaporation of the solvent. The residue obtained was dissolved in MeOH, passed through a SCX resin cartridge and the cartridge washed with MeOH. Then, the cartridge was treated with a 7N solution of NH3 in MeOH and the organic solution was concentrated under reduced pressure to give the title compound as a white powder. MS (ES+) C11H19IN4O: 351 (M+H)+.

Provenance & Evidence