HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Methylsulfonyl)benzaldehyde → HCID 178504760, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Methylsulfonyl)benzaldehyde | HCID 220376 | — |
| Reactant | 5-amino-3-((3-chlorophenyl)amino)-1H-pyrazole-4-carboxamide | HCID 86698956 | — |
| Catalyst | Piperidine | HCID 8082 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 178504760 | HCID 178504760 | — |
Reaction Steps
5-amino-3-((3-chlorophenyl)amino)-1H-pyrazole-4-carboxamide was then suspended in EtOH and 4-methylsulphonyl benzaldehyde (1 eq.) and piperidine (1 drop) were added. Stirred at reflux until intermediate was absent (HPLC). After reaction was complete (18 hrs) it was brought to room temperature and filtered to obtain product as a yellow powder. Powder was washed with EtOH. Product was allowed to dry under vacuum for 1 hr.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09365556B2 |
| Source dataset | uspto-grants-2016_06 |
| ORD ID | ord-149bfa01c90e4adba60cdbf160a79f32 |
| Source note | uspto-grants-2016_06 |