HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chloroquinoline → 4-quinolinepropanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chloroquinoline | HCID 69140 | — |
| Reactant | HCID 22376520 | HCID 22376520 | — |
| Reactant | HCID 68414407 | HCID 68414407 | — |
| Product | 4-quinolinepropanoic acid | HCID 264736 | — |
Reaction Steps
Prepared as 3-quinolin-4-yl-propionic acid trifluoroacetic acid salt from 4-chloroquinoline in analogy to the methods described for 3-isoquinolin-4-yl-propionic acid using the conditions described in J. Org. Chem. 2003, 68(18), 7077-7084, in the Heck reaction.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08202885B2 |
| Source dataset | uspto-grants-2012_06 |
| ORD ID | ord-004f194c29fb4551bd7ae66c5f11e797 |
| Source note | uspto-grants-2012_06 |