HCID 118343005, Verbindung → HCID 118383540, Verbindung
Reaktionsgleichung
[Cl:1][C:2]1[C:3]([O:17][CH3:18])=[N:4][CH:5]=[C:6]([Cl:16])[C:7]=1[CH2:8][CH2:9][NH:10][CH2:11][C:12]([CH3:15])([CH3:14])[CH3:13].C([O:21][C:22]([C@H:24]1[CH2:29][CH2:28][C@H:27]([N:30]2[C:34]([C:35]([F:38])([F:37])[F:36])=[C:33]([C:39](O)=[O:40])[CH:32]=[N:31]2)[CH2:26][C@H:25]1[CH3:42])=[O:23])C>>[Cl:1][C:2]1[C:3]([O:17][CH3:18])=[N:4][CH:5]=[C:6]([Cl:16])[C:7]=1[CH2:8][CH2:9][N:10]([CH2:11][C:12]([CH3:15])([CH3:13])[CH3:14])[C:39]([C:33]1[CH:32]=[N:31][N:30]([C@H:27]2[CH2:28][CH2:29][C@H:24]([C:22]([OH:23])=[O:21])[C@H:25]([CH3:42])[CH2:26]2)[C:34]=1[C:35]([F:38])([F:36])[F:37])=[O:40]Komponenten
3
Versuchsvorschrift
The title compound was prepared from N-(2-(3,5-dichloro-2-methoxypyridin-4-yl)ethyl)-2,2-dimethylpropan-1-amine and 1-((1S,3R,4S)-4-(ethoxycarbonyl)-3-methylcyclohexyl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid by procedures similar to those described in example 872. MS (ESI) 593.2, 595.1 [M+H]+.
Quellen und Nachweise
- ORD-Eintrag
- ord-07a94610856049f7ba2773512bef7d73
- Quelldatensatz
- uspto-grants-2016_06