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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 220279Generated: October 25, 2026

(2-Amino-3-chlorophenyl)amine → [3-(4-chloro-1H-benzoimidazol-2-yl)-propyl]methyl-amine

https://huagongshe.com/reaction/220279

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2-Amino-3-chlorophenyl)amineHCID 3462489—
Reactant[3-(5,6-dimethoxy-1H-benzoimidazol-2-yl)-propyl]-methyl-amineHCID 61363740—
Product[3-(4-chloro-1H-benzoimidazol-2-yl)-propyl]methyl-amineHCID 60787078—

Reaction Steps

Prepared from 3-chloro-benzene-1,2-diamine (J. Med. Chem. 1981, 24(1), 93-101) in analogy to the methods described for [3-(5,6-dimethoxy-1H-benzoimidazol-2-yl)-propyl]-methyl-amine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08202885B2
Source datasetuspto-grants-2012_06
ORD IDord-dec6873fbdc3443387e4eb4f4ad289b8
Source noteuspto-grants-2012_06